Citicoline plays an important role in many biochemical systems in the human body. It is especially important as a methyl-group donator, a cofactor for a variety of enzyme systems, and for phospholipid synthesis. Anecdotally, it may have similar effects to other Nootropic compounds.
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Citicoline (CDP-Choline) is known by a number of alternative names, including:
Citicoline is a brain chemical that is taken for its Nootropic-like effects to support healthy cognition. It is considered possibly safe for use by most people when taken at the recommended serving size for up to 90 days.
Some people have reported adverse effects like difficulty sleeping, headache, diarrhoea, high or low blood pressure, nausea, blurred vision and chest pain. Further research is required to fully understand the significance of the effects and adverse effects of CDP-Choline.
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Warning: There is not enough research about the safety of CDP Choline for pregnant and breastfeeding women. Do not use this supplement if you have any underlying medical conditions
CDP-choline is a nootropic compound that is essentially a prodrug for both choline and uridine, conferring both of those molecules to the body following oral ingestion of CDP-Choline. Specifically, the CDP-choline dissociates into choline and cytidine, with the cytidine then converting into uridine. CDP-choline is one of the three choline-containing phospholipids that can be orally supplemented (the other two being Alpha-GPC and phosphatidylcholine).
This supplement is catered towards preventing or treating memory impairments associated with aging due to the fact that both of the molecules it confers are neuroprotective and potentially enhance learning. While it appears to be more effective than phosphatidylcholine (PC) at this role, in part due to also increasing PC synthesis in the brain, its potency is somewhat comparable to that of Alpha-GPC.
CDP-choline has some other potential uses in relation to cognition. It is commonly used as a memory enhancer in youth, but despite some rodent studies suggesting that this is possible with oral CDP-choline, there are no human studies in youth at this point in time. One study has noted an increase in attention with low dose CDP-choline (which needs to be replicated), and CDP-choline may have roles as an anti-addictive compound against both cocaine and (preliminary evidence suggests) food as well.
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