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Ivermectin is used to treat river blindness (onchocerciasis), intestinal infection from threadworms (strongyloidiasis), and other kinds of worm infections.
Ivermectin is an anthelmintic. It works by interfering with the nerve and muscle functions of worms, by paralyzing and killing them.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms:
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of ivermectin in children weighing less than 15 kilograms (kg). Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ivermectin in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
It is important that your doctor check your or your child's progress at regular visits to make sure that the infection is cleared up completely. Blood tests may be needed to check for unwanted effects.
If you are being treated for river blindness, you may need retreatment and surgery to kill the adult parasite. You will need to see your doctor for follow up care.
If you are being treated for an intestinal infection from threadworms. You will need to have your bowel movements tested to make sure that the infection is gone. It is very important that you have these tests done as often as your doctor orders.
If your symptoms do not improve, or if they become worse, check with your doctor.
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This medicine may cause eye, skin, or other serious reactions (eg, Mazzotti reaction), in patients treated for river blindness. Check with your doctor right away if you have eye or eyelid irritation, pain, redness, or swelling, dizziness, lightheadedness, fainting, fast, pounding, or irregular heartbeat or pulse, fever, itching or skin rash, joint or muscle pain, stomach pain, swelling of hands, ankles, feet, or lower legs, swollen, painful, or tender lymph glands in neck, armpit, or groin, unusual tiredness or weakness.
This medicine may cause serious brain and nerve problems. Check with your doctor right away if you have change in consciousness, confusion about identity, place, and time, decreased awareness or responsiveness, loss of consciousness, or severe sleepiness.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Get emergency help immediately if any of the following symptoms of overdose occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-.
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Ivermectin has become a hot topic in recent months. Encouraged by claims that it is an effective treatment for COVID-19, people are asking their doctors for prescriptions of the anti-parasitic drug and in some cases taking a version of the medication intended for animals.
Here's what you need to know about ivermectin.
Ivermectin tablets have been approved by the U.S. Food and Drug Administration to treat people with certain parasitic infections, and an ivermectin solution is approved to treat people with head lice and rosacea. Another version and higher dosage of the drug is approved for use in animals as a de-wormer.
It has been hypothesized that ivermectin could slow or stop the novel coronavirus from replicating inside the human body. So far, clinical trials that have tested ivermectin's ability to prevent or treat COVID-19 have not convinced major public health organizations that the drug should be used for those purposes. More studies are ongoing.
'With COVID-19, many medications have been under evaluation to determine any potential use and potential efficacy, but we need more data before we use something like ivermectin for COVID-19,' said Christian Rojas Moreno, MD, an MU Health Care infectious disease doctor. 'The National Institutes of Health and societies for infectious diseases are not endorsing the use of ivermectin at any dose at this point for routine use in COVID-19.
'The only situations where humans with COVID-19 would get ivermectin would be in the context of a clinical trial. We hope we can get more data in the future, but as of today, we can't recommend ivermectin.'
Under no circumstances should you ever take any drug intended for animals. Rojas Moreno said the side effects of high doses of ivermectin include nausea, vomiting, diarrhea, dizziness, seizures and potentially even coma or death.
'That's where the danger comes,' Rojas Moreno said. 'If somebody is deciding to use animal ivermectin, because the dose may be much higher, the potential for toxicity is definitely higher.'
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