This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
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What Other Drugs Interact with Magnesium Oxide?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.
This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns, or for more information about this medicine.
This is a general overview. For more in-depth information, see our health professional fact sheet.
Magnesium is a nutrient that the body needs to stay healthy. Magnesium is important for many processes in the body, including regulating muscle and nerve function, blood sugar levels, and blood pressure and making protein, bone, and DNA.
The amount of magnesium you need depends on your age and sex. Average daily recommended amounts are listed below in milligrams (mg).
Life Stage Recommended Amount Birth to 6 months 30 mg Infants 7'12 months 75 mg Children 1'3 years 80 mg Children 4'8 years 130 mg Children 9'13 years 240 mg Teen boys 14'18 years 410 mg Teen girls 14'18 years 360 mg Men 400'420 mg Women 310'320 mg Pregnant teens 400 mg Pregnant women 350'360 mg Breastfeeding teens 360 mg Breastfeeding women 310'320 mgMagnesium is found naturally in many foods and is added to some fortified foods. You can get recommended amounts of magnesium by eating a variety of foods, including the following:
Magnesium is available in multivitamin/mineral supplements and other dietary supplements. Forms of magnesium in dietary supplements that are more easily absorbed by the body are magnesium aspartate, magnesium citrate, magnesium lactate, and magnesium chloride.
Magnesium is also included in some laxatives and some products for treating heartburn and indigestion.
The diets of many people in the United States provide less than the recommended amounts of magnesium. Men older than 70 and teenage girls and boys are most likely to have low intakes of magnesium. When the amount of magnesium people get from food and dietary supplements is combined, however, total intakes of magnesium are generally above recommended amounts.
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In the short term, getting too little magnesium does not produce obvious symptoms. When healthy people have low intakes, the kidneys help retain magnesium by limiting the amount lost in urine. Low magnesium intakes for a long period of time, however, can lead to magnesium deficiency. In addition, some medical conditions and medications interfere with the body's ability to absorb magnesium or increase the amount of magnesium that the body excretes, which can also lead to magnesium deficiency. Symptoms of magnesium deficiency include loss of appetite, nausea, vomiting, fatigue, and weakness. Extreme magnesium deficiency can cause numbness, tingling, muscle cramps, seizures, personality changes, and an abnormal heart rhythm.
The following groups of people are more likely than others to get too little magnesium:
Scientists are studying magnesium to understand how it affects health. Here are some examples of what this research has shown.
High blood pressure is a major risk factor for cardiovascular disease and stroke. Magnesium supplements might decrease blood pressure, but only by a small amount. Some studies show that people who have more magnesium in their diets have a lower risk of some types of heart disease and stroke. In many of these studies, however, it's hard to know how much of the effect was due to magnesium as opposed to other nutrients.
People with higher amounts of magnesium in their diets tend to have a lower risk of developing type 2 diabetes. Magnesium helps the body break down sugars and might help reduce the risk of insulin resistance (a condition that leads to diabetes). Scientists are studying whether magnesium supplements might help people who already have type 2 diabetes control their disease. More research is needed to better understand whether magnesium can help treat diabetes.
Magnesium is important for healthy bones. People with higher intakes of magnesium have a higher bone mineral density, which is important in reducing the risk of bone fractures and osteoporosis. Getting more magnesium from foods or dietary supplements might help older women improve their bone mineral density. More research is needed to better understand whether magnesium supplements can help reduce the risk of osteoporosis or treat this condition.
People who have migraine headaches sometimes have low levels of magnesium in their blood and other tissues. Several small studies found that magnesium supplements can modestly reduce the frequency of migraines. However, people should only take magnesium for this purpose under the care of a health care provider. More research is needed to determine whether magnesium supplements can help reduce the risk of migraines or ease migraine symptoms.
Magnesium that is naturally present in food and beverages is not harmful and does not need to be limited. In healthy people, the kidneys can get rid of any excess in the urine. However, magnesium in dietary supplements and medications should not be consumed in amounts above the upper limit, unless recommended by a health care provider.
The daily upper limits for magnesium from dietary supplements and/or medications are listed below. For many age groups, the upper limit appears to be lower than the recommended amount. This occurs because the recommended amounts include magnesium from all sources'food, beverages, dietary supplements, and medications. The upper limits include magnesium from only dietary supplements and medications; they do not include magnesium found naturally in food and beverages.
Ages Upper Limit for MagnesiumHigh intakes of magnesium from dietary supplements and medications can cause diarrhea, nausea, and abdominal cramping. Extremely high intakes of magnesium can lead to irregular heartbeat and cardiac arrest.
Yes. Magnesium supplements can interact or interfere with some medicines. Here are several examples:
Tell your doctor, pharmacist, and other health care providers about any dietary supplements and prescription or over-the-counter medicines you take. They can tell you if the dietary supplements might interact with your medicines or if the medicines might interfere with how your body absorbs, uses, or breaks down nutrients.
People should get most of their nutrients from food and beverages, according to the federal government's Dietary Guidelines for Americans. Foods contain vitamins, minerals, dietary fiber, and other components that benefit health. In some cases, fortified foods and dietary supplements are useful when it is not possible to meet needs for one or more nutrients (for example, during specific life stages such as pregnancy). For more information about building a healthy dietary pattern, see the Dietary Guidelines for Americans and the U.S. Department of Agriculture's (USDA's) MyPlate.
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