Abstract : Rhodiola rosea (rose root) belonging to the family Crassulaceae is a popular medicinal plant in Russia, Scandinavia, and many other countries. Extracts of the roots of this plant have been found to favorably affect a number of physiological functions including neurotransmitter levels, central nervous system activity, and cardiovascular function. It is being used to stimulate the nervous system, decrease depression, enhance work performance, eliminate fatigue, and prevent high-altitude sickness. Most of these effects have been ascribed to constituents such as salidroside (rhodioloside), rosavins, and p-tyrosol. It has also been found to be a strong antioxidant and anticarcinogen due to the presence of several phenolic compounds. Adaptogens are plant extracts that allow an organism to counteract adverse physical, chemical, and biological stressors by generating nonspecific resistance. Adaptogens are known to increase the availability of energy during the day, reduce stressed feelings, increase endurance, and increase mental alertness. This multipurpose medicinal plant (R. rosea), with adaptogenic properties that increase the body's nonspecific resistance and normalize functions, has been traditionally grown and used in Russia and Mongolia. Due to increasing consumer demands toward natural health products and the growing interests in the secondary metabolites of plants and their application in biotechnology and therapy, much focus has been put on the rose root and its medical properties. The rose root imparts normalizing influences on adverse physical, chemical, and biological disturbances but is otherwise innocuous. In India, the plant has been growing wild in the high altitudes of the Himalayas. The Defence Research and Development Organization in India has taken on the responsibilities of its conservation, as well as the development of multiple management practices and the development of health foods, supplements, and nutraceuticals in India.
Introduction : Controlled studies are warranted to explore its use in antidepressant augmentation, disorders of memory and cognition, attention deficit disorder, traumatic brain injury, Parkinson's disease, protection against arrhythmias, sports performance, aviation and space medicine (enhancing physical and mental performance while reducing stress reactions), endocrine disorders (infertility, premenstrual disorder, menopause), sexual dysfunction, disorders of the stress-response system (fibromyalgia, chronic fatigue syndrome, and posttraumatic stress disorder), and enhancement of chemotherapy/radiation with amelioration of toxicity.
During evolution, R. rosea has adapted to the harsh conditions of high altitude (extreme cold, low oxygen, little rainfall, and intense irradiation from the sun) by producing a group of powerful protective compounds that have diverse beneficial effects in animals and humans. One is struck by the versatility of R. rosea, from its description in Greek medicine y ago to its use by 21stcentury cosmonauts. It is time for modern research, using controlled clinical trials, to develop the potential medical applications for this unique phyto-adaptogen. There is immense potential to develop health foods, foods supplements, herbal preparations, and drugs from this unique herb from high altitudes. Its potential for development of radioprotectants - needed in today's world - is immense. Promotion of its production and protection would be beneficial to society.
Conclusion (partial) There is immense potential to develop health foods, foods supplements, herbal preparations, and drugs from this unique herb from high altitudes. Its potential for development of radioprotectants'needed in today's world' is immense. Promotion of its production and protection would be beneficial to society.
Controlled studies are warranted to explore its use in antidepressant augmentation, disorders of memory and cognition, attention deficit disorder, traumatic brain injury, Parkinson's disease, protection against arrhythmias, sports performance, aviation and space medicine (enhancing physical and mental performance while reducing stress reactions), endocrine disorders (infertility, premenstrual disorder, menopause), sexual dysfunction, disorders of the stress-response system (fibromyalgia, chronic fatigue syndrome, and posttraumatic stress disorder), and enhancement of chemotherapy/radiation with amelioration of toxicity. During evolution, R. rosea has adapted to the harsh conditions of high altitude (extreme cold, low oxygen, little rainfall, and intense irradiation from the sun) by producing a group of powerful protective compounds that have diverse beneficial effects in animals and humans.
Rhodiola rosea: A Versatile Adaptogen - Farhath Khanum, Amarinder Singh Bawa, and Brahm Singh, Institute of Food Technologists, Vol. 4,
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